Conolidine’s analgesic results stem from its conversation with non-opioid pain pathways. As opposed to opioids, which bind to µ-opioid receptors within the central anxious system, conolidine modulates alternate molecular targets. A Science Improvements examine found that conolidine interacts Using the atypical chemokine receptor ACKR3/CXCR7, which regulates opioid peptide availability. https://leftbookmarks.com/story20660648/not-known-factual-statements-about-alternative-natural-pain-relief-to-replace-traditional-painkillers