At an oral dose of 2000 mg/kg/day in rats, maternal toxicity and deaths were being viewed with an increased incidence of early fetal resorption; spontaneous abortions transpired in cynomolgus monkeys on the maternally toxic oral dose of 2000 mg/kg/day; there are no suitable and very well-controlled trials in pregnant women; https://englandt009gsc2.blogars.com/profile