There exists a launch of norepinephrine within the descending inhibitory bulbospinal neurons that binds to alpha-two-receptors from the dorsal horn to minimize afferent discomfort transmission and develop analgesia. As a result, medications like clonidine that target alpha-2 receptors can influence the transmission of pain. Could be presented as monotherapy https://chesterg046lhb4.activosblog.com/profile