Inhibition of focal adhesion kinase (FAK) rescued SERT function in synapses of KI mice, demonstrating that constitutive active FAK signaling downstream from the Pro32Pro33 integrin αvβthree suppresses SERT action. Our reports establish a posh regulation of 5-HT homeostasis and behaviors by integrin αvβthree, revealing an essential part for integrins in https://frankx986cnx7.wonderkingwiki.com/user