Environmental or self-antigens and homotypic interactions result in BCR and Toll-like receptor (TLR) signaling, amplifying the response of CLL cells to other indicators from your microenvironment and increasing the activation of anti-apoptotic and proliferation pathways.31,32 Genomic experiments have discovered recurrent mutations in genes regulating tumor cell-microenvironment intera... https://danielr615ycl9.bligblogging.com/profile