Injectable codeine is accessible for subcutaneous or intramuscular injection only; intravenous injection is contraindicated, as this may end up in nonimmune mast-cell degranulation and resulting anaphylactoid response. Codeine suppositories can also be marketed in some countries. In Eire, new restrictions arrived into effect on 1 August 2010[ninety] relating to codeine, https://codeingil.com/